Article title: Hereditary spastic paraplegia Author: Tala Mohammad Editors: Haneen Al-Abdallat, Haneen A. Banihani Reviewer: Ethar Hazaimeh Keywords: Hereditary, Ataxia, Spastic, Motor, Neurodegenerative Overview and epidemiology Hereditary spastic paraplegias (HSPs) are a group of neurodegenerative disorders characterized by motor neuron degeneration in the lower extremities,1 with relative sparing of the rest of the body.2 It is also known as Strumpell-Lorrain syndrome. HSPs are generally considered non-life-threatening but are linked with a poor quality of life.3 They can be classified as pure or complex,4 the latter associated with additional neurological features.2 HSP is further divided according to the mode of inheritance, […]
Article topic: Cluster Headache Author: Tala Mohammad Editors: Nicola AL-Madani, Ethar Hazaimeh Keywords: Unilateral, trigeminal, episodic, chronic, headache, sumatriptan. Overview Cluster headache is a primary headache disorder, part of the family of trigeminal autonomic cephalalgias (TCAs), characterized by excruciating unilateral pain, often involving the supraorbital, retro-orbital, or temporal regions1. All TACs share the common feature of unilateral pain, accompanied by prominent cranial parasympathetic autonomic features, which are usually ipsilateral to the headache2. Attacks of cluster headache may range between 15-180 minutes, occurring anywhere between once every other day to up to eight times per day2. Cluster headache has also been […]