Article topic: High-Grade Glioma (Anaplastic Astrocytoma) Author;  Shroug Naser Al Hamdan Editor: Ethar Hazaimeh Keywords: anaplastic astrocytoma, malignant astrocytoma.   Overview Anaplastic astrocytoma (AA) is a diffusely infiltrating, malignant, astrocytic, primary brain malignant tumor with a median age of onset of 41 years [1]. Presently, an anaplastic astrocytoma is defined by the histologic characteristics of nuclear atypia, increased cellularity, significant proliferative activity as manifested by mitoses, and lacking either endothelial proliferation or necrosis [1]. Nearly, a quarter of anaplastic astrocytoma (AA) arise as a de novo tumor, whereas it is estimated that three quarters are a consequence of transformation from […]

Article topic: Low grade glioma  By: Shoroug Naser Al Hamdan Key word: Low grade glioma ,grade II brain tumor . Scientific editing : Dr.Omar Jbara  Linguistic editing : Philip Sweidan   DEFINITION The term low-grade glioma (LGG) refers to tumors classified by the World Health Organization (WHO) as grades I and grade II, including oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas [1]. WHO grade I LGGs are truly benign tumors that can be treated with surgical removal . On the other hand, WHO grade II LGGs are diffuse and infiltrative intracerebral lesions rarely curable , [2] they are slowly progressing conditions that […]