Article topic: Approach to Central Pontine Myelinolysis (CPM) Authors: Nancy Zrara, Omar Al Khatib Editor: Lubna AL-Rawabdeh Reviewer: Rania Al-Bataineh Keywords: CPM, hyponatremia, 0smotic demyelinating syndrome, central nervous system (CNS) Abstract Central Pontine Myelinolysis (CPM) is a demyelinating disease of the pons that was first described by Adams et al. in 1959. The main cause of CPM is the rapid correction of hyponatremia, alongside other etiologies including alcoholism, liver disease, transplantation, malnutrition, and burns. CPM pathogenesis starts from the adaptation of the brain to hyponatremia by losing many electrolytes that cannot be recaptured during the rapid sodium correction, leading to […]