Article topic: Lambert Eaton myasthenic syndrome (LEMS) Authors: Lobana Nabeel Mahdawi, Samah Zeidan Alajjawe Editor: Lubna AL-Rawabdeh Reviewer: Ethar Hazaimeh keywords: Neuromuscular junction, Lung Cancer, Autoantibodies, LEMS. Overview Lambert Eaton myasthenic syndrome (LEMS) is considered a rare neuromuscular junction disorder that could be an idiopathic autoimmune disorder or a paraneoplastic phenomenon [1]. It is a rare disease with a well-characterized pathogenesis [2]. autoantibodies against presynaptic voltage-gated calcium channels that are present in the neuromuscular junction are the primary underlying mechanisms [3]. More than half of cases present as a paraneoplastic form associated with a malignant tumor which is a small cell lung carcinoma […]

Please wait...