Article Topic: Miller-Fisher Syndrome Authors: Joyce Labaky, Jim Dagher Editors: Odette El Ghawi, Joseph Akiki Reviewer: Ethar Hazaimeh Keywords: Miller Fisher Syndrome, Guillain Barré Syndrome, peripheral neuropathy, autoimmune disorder Abstract Miller-Fisher Syndrome (MFS) is a rare, immune-mediated neurological disorder that is considered a variant of Guillain Barré Syndrome (GBS). It is primarily characterized by the clinical triad of ophthalmoplegia, ataxia, and areflexia. The pathophysiology of MFS is associated with autoantibodies, particularly anti-GQ1b antibodies, which target gangliosides at the neuromuscular junction, especially in areas rich in these gangliosides, such as the oculomotor nerves. MFS typically follows a preceding viral or bacterial […]
Please wait...