Article Topic: Central Pontine Myelinolysis. Author: Hosam Aldeen Katba Badar. Editors: Almutazballlah Qablan, Sadeen Eid. Reviewer: Ethar Hazaimeh Keywords: pons, demyelination, hyponatremia, osmolyte, electrolyte. Introduction Central pontine myelinolysis (CPM) is a neurological disorder defined as well-formed symmetric damage to the myelin and to the oligodendrocytes in the pons with the preservation of neurons and axons. Extrapontine myelinolysis (EPM) on the other hand, is characterized by lesions in the thalamus, cerebral cortex, striatum, and other areas 1. Typical clinical manifestations of myelinolysis include paralysis, dysarthria, and altered mental status 2. Typically, CPM is secondary to the rapid correction of hyponatremia 1. […]