Article title: Creutzfeldt- Jakob disease (CJD) Author: Balqees Jboul Reviewer: Lobana Mahdawi Overview Creutzfeldt-Jakob disease is a rare and fatal transmissible neurodegenerative disorder that the underlying cause of it is misfolded prion proteins (PrPSc). Effective therapeutics for the disease are not available and the accurate diagnosis of the disease can be challenging, but there is a palliative treatment that tries to keep the person as comfortable as possible and reduce the symptoms, The most common form of human prion disease is sCJD with incidence around 1.5 to 2.0 per million person-years. (1) Pathogenesis  Different types of CJD may be different […]