Title: Neurofibromatosis type 1 Author: Shahed Aldalahmeh Editor: Aseel Rabadi, Sadeen Eid Reviewer: Neebal Algallab, Ethar Hazaimeh Keywords: Neurofibromatosis, Neurocutaneous syndromes Overview Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder, also known as Von Recklinghausen disease (VRD) or Peripheral Neurofibromatosis [1]. It significantly impacts the nervous system, eyes, skin, and bones. Affected individuals develop both benign and malignant tumors such as neurofibromas, malignant peripheral nerve sheath tumors, and gliomas. It has a prevalence of 1/3,000 and it is higher in young children than adults [2]. It has one of the highest mutation rates in humankind [3]. Risk Factors NF1 affects […]