Article topic: Antidepressant discontinuation syndrome Author: Serena Semaan Editors: Nancy Zrara, Christie Dib Reviewer: Lobana Mahdawi  Introduction Antidepressant drugs are commonly prescribed for depression and anxiety, as well as for obsessive-compulsive disorder (OCD), insomnia, chronic pain, erectile dysfunction (ED), smoking cessation, migraine, and Attention-deficit/hyperactivity disorder (ADHD). However, these drugs can lead to unpleasant effects during the discontinuation process, known as antidepressant discontinuation syndrome (ADS). ADS may occur following treatment with all types of antidepressants, although most literature focuses on selective serotonin reuptake inhibitors (SSRIs). DSM-5-TR enlists ADS among the “medication-induced movement disorders and adverse effects of medication”.The signs of ADS […]